RebrAIn Scope

Rebrain helps to treat Parkinson's disease and EssentiAl Tremor

RebrAIn offers a technology that helps neurosurgeons identifying brain regions to operate on patients with Parkinson’s disease and essential tremor. Using an Artificial Intelligence algorithm and a collaborative registry of health data, RebrAIn simplifies and standardizes procedures with the aim of increasing the number of treated patients worldwide.


Testimony of a ParkinsonIAN Patient operated on with the help of Rebrain'S technology
Testimony of an Essential Tremor Patient operated on with the help of Rebrain'S technology

RebrAIn Technology

Rebrain, a Bordeaux French Tech startup with global ambitions!

Rebrain learns from success to reproduce success

Rebrain Technology
  • Learns from patients with post-op clinical improvement
  • Uses Artificial Intelligence to reproduce success
  • Works with the simplest MRI sequences
  • Provides marked MRI in the regions of interest
The Rebrain Service
  • Processes the MRI on the cloud
  • Allows a secure exchange of health data in compliance with the GDPR
  • Hosts data on HDS (Health Data Hosting) certified servers

From facial recognition to brain recognition

Starting from a T1, 1.5 T MRI without injection, the OptimDBS software re-axes the MRI then recognizes 18 anatomical structures per side in a semi-automatic way. After having “recognized” the brain as facial recognition systems recognize faces, it is then possible to apply the mathematical metamodel based on artificial intelligence which predicts the targets and marks them on the MRI. It is this marked MRI that is sent back to the healthcare centers to help in planning neurosurgical procedures.

RebrAIn Care

ReBrain aims to simplify & standardize neurosurgical procedures Aiming to treat more patients worldwide.

A simpler, less traumatic surgery

With the use of the OptimDBS software, the physicians will be able to free themselves from intraoperative electrophysiology (Clinical studies are ongoing).

More patients treated worldwide

This simplification will lead to an increase in the number of patients operated worldwide.

Patients as actors of their own treatment

A transparent community where patients know what treatments can be offered to them and with what results.


RebrAIn Team


Emmanuel Cuny

Co-founder, CMO & Board President
Professor of Neurosurgery Bordeaux University Hospital Board member Vygon.

Nejib Zemzemi

Co-founder, CSO & CTO
Researcher at Inria; 100 Publications in mathematical inverse problems.

David Caumartin

Global P& L., Public Company CEO, VP France Biotech,EIT Health Advisor, FUS Senior Partner.
Strategic Board

Emmanuel Cuny​

Co-founder, CMO & Board President​

Nejib Zemzemi

Co-founder, CSO & CTO

David Caumartin


Vincent Pretet


Catherine Boule


Amine Benamoussa


Tom Beauvironnet

Scientific Board

A team of 12 employees with multidisciplinary and complementary expertise in Clinical practice, Data Science, Software development, Market access, Business and Quality & Regulatory Affairs.

They trust us

RebrAIn Invest

Become an actor in medical innovation!

Beyond the financial aspect, we are looking for investors who believe in our innovation and its positive impact in the advancement against neurodegenerative diseases. Investing in RebrAin means joining its ecosystem and participating in medical breakthroughs and patients’ well-being.

To find out more about the financial and commercial aspects of the startup, the project’s technological innovation, the opportunities at stake and the global market size, we invite you to contact us so that we can present our strategy to you.

They support us

The Nouvelle Aquitaine Region and the European Union support RebrAIn within the framework of the ERDF/ESF Operational Programme 2021-2027

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