Sub-millimetric, patient-specific brain targeting for functional neurosurgery and real-world outcomes in Parkinson’s Disease and Essential Tremor.

REBRAIN AT WSSFN 2026

A second expert view to support targeting decisions.

Discover Rebrain's patient-specific approach, designed to complement the neurosurgeon's expertise.

September 30 to October 3Palais du Pharo, Marseille

Lunch Symposium with Rebrain
Thursday, October 1, 12:50 to 14:20 | Room 76

Patient-specific brain targeting
for functional neurosurgery

Real-world outcomes that reshape care
for Parkinson’s Disease and Essential Tremor

Rebrain is a spin-off of the University Hospital of Bordeaux and the Inria, based in the EU and the US, created by Professor Emmanuel Cuny, Neurosurgeon, and Professor Nejib Zemzemi, Researcher at Inria in Applied Mathematics, after 10 years of academic research and 2 theses.

Rebrain’s service is a best-in-class, supervised AI-driven solution that streamlines complex, patient-specific neurosurgery by providing faster, simpler, and safer treatment through augmented neuromodulation planning.

Regulatory

CE marked,
FDA 510(k) cleared

Adoption

60+ sites
worldwide

Indications

Parkinson’s disease (STN),
Essential tremor (VIM)

Volume

1 000+ targeting
operations performed

From T1 MRI upload to surgery planning,
Rebrain services streamlines the pre-surgical planning process.

We have developed a targeting service that uses supervised AI algorithm & health data exchange platform to simplify and standardize neurosurgical procedures.

Our solution seamlessly integrate supervised AI-guided targeting into any workflow to streamline and standardize neurosurgical procedures.

1

Upload

VIM or STN, left, right, or bilateral

2

Data Processing

18 landmarks per hemisphere

3

Download

ready-to-use MRI

Online secured portal
Answer 5 case questions

Rebrain Neuro operator supervised
Crosshair on desired target(s)

Raw DICOM with target overlay
Works with your existing setup

With Rebrain, we aim to enhance efficiency and peace of mind
for neurosurgeons and staff by providing millimetric MRI-guided
targeting of the STN or VIM based on a health data exchange platform.

Seamless integration

Surgery
under GA

Fast
workflow

Precise
surgery

Safe and efficient

Real Life impact

Testimony of a Parkinsonian patient treated on with the help of Rebrain’ services

Testimony of an Essential Tremor patient treated on with the help of Rebrain’ services

Real Life impact

Testimony of a Parkinsonian patient treated on with the help of Rebrain’ services

Testimony of an Essential Tremor patient treated on with the help of Rebrain’ services

Marked MRI
worldwide

best-in-class
clinical data

Key anatomical
landmarks

Our latest public updates

Rebrain at WSSFN 2026

Rebrain at WSSFN 2026

Rebrain will take part in the 2026 World Society for Stereotactic and Functional Neurosurgery Congress (WSSFN), held at the Palais du Pharo in Marseille from September 30 to October 3. You will find the team, in the exhibition foyer next to the main entrance. Born...

Rebrain x Worldwide Dystonia Research Center

Rebrain x Worldwide Dystonia Research Center

Partnership aims to develop next-generation data-driven models for personalized deep brain stimulation (DBS) targeting, expanding clinical applications from Parkinson’s disease and essential tremor to dystonia and severe pediatric dystonia with global scalability...