Patient-specific brain targeting
for functional neurosurgery
Real-world outcomes that reshape care
for Parkinson’s Disease and Essential Tremor
Rebrain is a spin-off of the University Hospital of Bordeaux and the Inria, based in the EU and the US, created by Professor Emmanuel Cuny, Neurosurgeon, and Professor Nejib Zemzemi, Researcher at Inria in Applied Mathematics, after 10 years of academic research and 2 theses.
Rebrain’s service is a best-in-class, supervised AI-driven solution that streamlines complex, patient-specific neurosurgery by providing faster, simpler, and safer treatment through augmented neuromodulation planning.
Regulatory
CE marked,
FDA 510(k) cleared
Adoption
60+ sites
worldwide
Indications
Parkinson’s disease (STN),
Essential tremor (VIM)
Volume
1 000+ targeting
operations performed
From T1 MRI upload to surgery planning,
Rebrain services streamlines the pre-surgical planning process.
We have developed a targeting service that uses supervised AI algorithm & health data exchange platform to simplify and standardize neurosurgical procedures.
Our solution seamlessly integrate supervised AI-guided targeting into any workflow to streamline and standardize neurosurgical procedures.
* Rebrain’ service leverages CE Marked and FDA 510(k) cleared Software as a Medical Device (SaMD), OptimMRI and OptimDBS.
1
Upload
VIM or STN, left, right, or bilateral
2
Data Processing
18 landmarks per hemisphere
3
Download
ready-to-use MRI
Online secured portal
Answer 5 case questions
Rebrain Neuro operator supervised
Crosshair on desired target(s)
Raw DICOM with target overlay
Works with your existing setup
With Rebrain, we aim to enhance efficiency and peace of mind
for neurosurgeons and staff by providing millimetric MRI-guided
targeting of the STN or VIM based on a health data exchange platform.
Seamless integration
Surgery
under GA
Fast
workflow
Precise
surgery
Safe and efficient
Real Life impact
Testimony of a Parkinsonian patient treated on with the help of Rebrain’ services
Testimony of an Essential Tremor patient treated on with the help of Rebrain’ services
Real Life impact
Testimony of a Parkinsonian patient treated on with the help of Rebrain’ services
Testimony of an Essential Tremor patient treated on with the help of Rebrain’ services
Marked MRI
worldwide
best-in-class
clinical data
Key anatomical
landmarks
Our latest public updates
MedTech Strategist Features RebrAIn’s Precision Targeting Solutions for Parkinson’s Disease
We are delighted to share that MedTech Strategist has featured RebrAIn in their latest issue.The article explores how our supervised AI-driven platform, OptimMRI, simplifies precision targeting for Deep Brain Stimulation (DBS) in Parkinson’s Disease. By enhancing...
Focused Ultrasound Foundation Highlights RebrAIn’s AI Innovations in Neurosurgery
We are excited to share that the Focused Ultrasound Foundation has featured RebrAIn for our pioneering use of artificial intelligence in brain targeting. The article details how our supervised AI-driven platform, Optim MRI, enhances precision and effectiveness in...
L’Usine Digitale Highlights RebrAIn’s €3.7 Million Funding for Supervised AI-Driven Neurosurgery
We are pleased to share that L'Usine Digitale has featured RebrAIn for securing €3.7 million to advance our supervised AI-driven software. This innovative platform is designed to simplify the work of neurosurgeons by enhancing the precision and efficiency of Deep...


